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Faculty Leader: Manish Patankar
Facility Manager: Dagna Sheerar
Recent Publications
Decidual-Placental Immune Landscape During Syngeneic Murine Pregnancy
Adaptive immune system, principally governed by the T cells-dendritic cells (DCs) nexus, is an essential mediator of gestational fetal tolerance and protection against infection.
September 19, 2018Computational flow cytometry analysis reveals a unique immune signature of the human maternal‐fetal interface
Decidual immune dysregulation is thought to underlie major pregnancy disorders; however, incomplete understanding of the decidual immune interface has hampered the mechanistic investigation.
October 14, 2017- More Flow Publications
Scientific Accomplishments
Analytical Flow Cytometry Services
Response Monitoring in Clinical Research Trials
- FLOW supported the work of Douglas McNeel (DT) and colleagues in monitoring intracellular cytokine expression in T cells from patients receiving DNA vaccine encoding prostatic acid phosphatase using analytical flow cytometry
- FLOW provided real-time monitoring of immune response in patients recruited in a DNA vaccine clinical
- McNeel, DG. et al. Clin Can Res (2014) 20:3692-704
- R21 CA132267 and P30 CA014520 supplement
Cell Sorting Services
Supporting Translational Cancer Research
- FLOW supported the work of Jing Zhang (DT) and colleagues in monitoring MEK/ERK signaling in murine myeloproliferative neoplasms
- Hematopoietic Stem Cells and Myeloproliferative Progenitor Cells isolated by FACS and analyzed by flow cytometry for phosphorylation states of MEK and ERK pathways
- Kong, G., et al. J Clin Invest (2014) 124:276-273.
- 1R01CA152108 and 1R01HL113066
Imaging Cytometry Services
Supporting Basic Cancer Research
- FLOW supported the research of William Burlingham (TM) and colleagues in monitoring presentation of alloantigens on dendritic cells in murine microchimerism model to understand immune tolerance
- Dendritic Cells presenting antigens were detected and quantified by Imaging Cytometry and Flow Cytometry
- William Bracamonte-Baran et al. PNAS 2017;114:1099-1104
- 2R01-AI066219