The LBMS is equipped with seven different state-of-the art mass spectrometry (MS) instruments, enabling both targeted analysis of specific metabolites and discovery global metabolite profiling. For relative or absolute quantification of specific metabolites, LBMS has developed targeted assays on triple quadruple LC-MS systems and single quadrupole GC-MS systems with throughput of 16-40 samples/day. Targeted assays include panels for central metabolism (e.g., TCA cycle, glycolysis), methionine pathway metabolites, amino acids, primary and secondary bile acids, sugars and fatty acids. Projects depending on the measurement of key metabolites not routinely measured with standard assays can be considered for custom assay development.