UWCCC Research TEST
Resource for Researchers

Inventory & Requests

Forms for all TSB BioBank requests (inventory and service) can be found at our iLab page.

The TSB BioBank inventory is updated on a quarterly basis and includes, but is not limited to, tumor and normal tissues from a variety of body sites and histologies with matched and unmatched blood from patients with cancer, as well as tissue from patients with non-cancerous conditions and blood from healthy volunteers.

See the below sections for more information:

Inventory

Questions with respect to the TSB BioBank inventory can be directed to the TSB BioBank Facility Manager via the Inventory Inquiry Form in iLab. Inventory is updated on a quarterly basis.

TSB Biobank Specimens (Inventory as of Thursday, Jan 17, 2019)
 Blood – MALIGNANT – PRIMARY  Blood – OTHER  Bone Marrow – MALIGNANT  Bone Marrow – OTHER  Tissue – MALIGNANT – PRIMARY  Tissue – OTHER Other – MALIGNANT – PRIMARY Total CASE TYPE
Breast Breast 0 4 0 2 344 1083 0 1433
SUBTOTAL Breast 0 4 0 2 344 1083 0 1434
Central Nervous System Brain 0 8 0 1 0 1 0 10
Spinal Cord 0 0 0 0 0 2 0 2
SUBTOTAL Central Nervous 0 8 0 1 0 3 0 12
Digestive System Ampulla of Vater 17 34 0 0 7 25 0 83
Anus 0 8 0 0 1 6 0 15
Appendix 9 71 0 0 4 58 0 142
Colon and Rectum 24 703 0 1 202 790 0 1720
Esophagus 0 32 0 0 13 27 0 72
Extrahepatic Bile Ducts 5 35 0 0 2 12 0 54
Gallbladder 13 229 0 0 4 72 0 318
Liver 23 201 0 0 63 135 0 422
Pancreas – GI 148 473 0 0 115 256 0 992
Small Intestine 4 73 0 0 22 100 0 199
Stomach 44 151 0 0 42 83 0 320
SUBTOTAL Digestive System 287 2010 0 1 475 1564 0 4337
Endocrine Adrenal Gland, Endocrine 0 12 0 0 12 82 0 106
Other, Endocrine 0 0 0 0 1 4 0 5
Parathyroid 0 0 0 0 0 34 0 34
Thyroid Gland – Endocrine 3 20 0 0 134 869 0 1026
SUBTOTAL Endocrine 3 32 0 0 147 989 0 1171
Genitourinary Kidney 8 9 0 0 191 318 0 526
Penis, Genitourinary 0 0 0 0 1 2 0 3
Prostate Gland 0 0 0 0 515 981 0 1495
Retroperitoneum 0 17 0 0 8 6 0 31
Testis 0 0 0 0 28 45 0 73
Ureter 0 0 0 0 4 11 0 15
Urethra 0 0 0 0 1 0 0 1
Urinary Bladder 0 0 0 0 78 173 0 251
SUBTOTAL Genitourinary 8 26 0 0 826 1535 0 2395
Gynecologic Fallopian Tube 0 0 0 0 8 27 0 35
Ovary 0 12 0 0 232 594 0 838
Uterine Cervix 0 0 0 0 8 21 0 29
Uterus 0 8 0 0 485 746 0 1239
Vagina 0 4 0 0 1 5 0 10
Vulva 0 0 0 0 5 8 0 13
null 0 0 0 0 1 1 0 2
SUBTOTAL Gynecologic 0 24 0 0 740 1402 0 2166
Head and Neck Aerodigestive Tract 0 16 0 0 8 7 0 31
H&N Unknown Primary 4 42 0 0 2 6 0 54
Larynx 23 69 0 0 17 14 0 123
Lip and Oral Cavity 134 255 0 0 58 63 0 510
Nasal Cavity and Paranasal 18 32 0 0 6 9 0 65
Pharynx 46 32 0 0 6 13 0 97
Salivary Gland 0 40 0 0 17 42 0 99
Thyroid Gland – H&N 0 28 0 0 6 5 0 39
Tonsil 8 44 0 0 3 200 0 255
SUBTOTAL Head and Neck 233 558 0 0 123 359 0 1273
Hematologic System Bone Marrow 197 41 585 451 2 2 0 1278
Extra-nodal (excluding bone 0 1 0 6 5 1 0 13
Hematologic System 29 90 4 7 18 2 0 150
Lymph Node 41 173 7 150 86 74 1 532
Spleen 21 24 0 3 5 51 0 104
SUBTOTAL Hematologic System 288 329 596 617 116 130 1 2077
Neuroendocrine Neuroendocrine, 15 43 0 0 23 52 0 133
Pancreas – Neuro 25 77 0 0 18 57 0 177
SUBTOTAL Neuroendocrine 40 120 0 0 41 109 0 310
Skin Skin 48 225 0 0 12 110 0 395
SUBTOTAL Skin 48 225 0 0 12 110 0 395
Soft Tissue and Bone Bone 4 8 0 0 8 16 0 36
Mesothelium 0 10 0 0 2 3 0 15
Muscle 0 0 0 0 6 28 0 34
Omentum 0 4 0 0 3 2 0 9
Other 5 36 0 0 3 17 0 61
Soft Tissue 46 105 0 0 128 238 0 517
SUBTOTAL Soft Tissue and Bone 55 163 0 0 150 304 0 672
Thorax Adrenal Gland 0 0 0 0 0 2 0 2
Heart 0 0 0 0 1 14 0 15
Lung 0 180 0 1 222 396 0 799
Mediastinum 0 0 0 0 0 5 0 5
Pleura 0 1 0 0 1 7 0 9
Soft Tissue, Thorax 4 0 0 0 8 8 0 20
Thymus 0 0 0 0 3 20 0 23
SUBTOTAL Thorax 4 181 0 1 235 452 0 873
Unknown Primary null 0 0 0 0 1 1 0 2
SUBTOTAL Unknown Primary 0 0 0 0 1 1 0 2
TOTAL 966 3680 596 622 3210 8042 1 17117

Body Site: Selected sites or histologies of interest

Count of Cases: Bold totals include all specimen pathology statuses (benign, malignant, etc.) Non-bold totals represent a partial selection of available malignant primary cases.

*Cases may overlap

**A separate Brain Bank exists

Biospecimen Request

Click on the tab that best describes your request and follow the instructions.

Please note: The TSB BioBank does not currently distribute paraffin embedded tissue samples. Please direct paraffin embed tissue requests to the director for Surgical Pathology.

Follow these instructions if you are requesting biospecimen samples under the BioBank’s “Honest Broker” IRB protocol (Protocol 2016-0934), which allows distribution of biospecimens with coded patient data.  This accommodates any studies that do not need patient identifiable data.

  1. Submit the Inventory Inquiry Form via iLab which will be sent to the TSB BioBank Facility Manager to ensure there are sufficient banked specimens available for the proposed project.
  2. The TSB BioBank Facility Manager will inform you if there are sufficient banked specimens available. If specimens are available, the TSB BioBank Facility Manager will ask the investigator to send their research proposal to be reviewed by the Disease Specific Advisory sub-committees and the TSB BioBank Faculty Leader, who will assess the proposal’s biological material request and review the prioritization of specimens.
  3. The TSB BioBank Facility Manager will inform the investigator of the committee’s response within 2 weeks.
  4. Once notified, please submit the Formal Biospecimen Request Form.
  5. For requests that receive approval, disbursement of samples will usually occur within three weeks of submitting the formal request.

Follow these instructions if you are requesting biospecimen samples that require patient identifiable information (i.e., do not fall under the BioBank’s “Honest Broker” IRB), and IRB approval has already been obtained by the study PI.

  1. Submit the Inventory Inquiry Form via iLab which will be sent to the TSB BioBank Facility Manager to ensure there are sufficient banked specimens available for the proposed project.
  2. The TSB BioBank Facility Manager will inform you if there are sufficient banked specimens available. If specimens are available, the TSB BioBank Facility Manager will request a copy of your IRB approved protocol. The Disease Specific Advisory Sub-Committees and the TSB BioBank Faculty Leader then review the IRB approved protocol to assess the protocol’s biological material request and review the prioritization of specimens.
  3. The TSB BioBank Facility Manager will inform the investigator of the committee’s response within 2 weeks.
  4. Once notified, please submit the Formal Biospecimen Request Form via iLab.
  5. Biospecimen disbursement will usually occur within two weeks of receiving the Formal Biospecimen Request Form and approved IRB protocol.

Follow these instructions if you are requesting biospecimen samples that require patient identifiable information (i.e., do not fall under the BioBank’s “Honest Broker” IRB), and IRB approval has NOT yet been obtained by the study PI.

  1. Submit the Inventory Inquiry Form via iLab which will be sent to the TSB BioBank Facility Manager to ensure there are sufficient banked specimens available for the proposed project.
  2. The TSB BioBank Facility Manager will inform you if there are sufficient banked specimens available. If specimens are available, the TSB BioBank Facility Manager will request a copy of your protocol. The Disease Specific Advisory Sub-Committees and the TSB BioBank Faculty Leader will then review the protocol to assess the protocol’s biological material request and review the prioritization of specimens.
  3. The TSB BioBank Facility Manager will inform the investigator of the committee’s response within 2 weeks.
  4. If the research proposal is approved by the TSB BioBank, then PRMC and IRB approval will be required prior to sample distribution. Please see the UW Carbone Cancer Center internal PRMC website (NetID required, contact crco@uwcarbone.wisc.edu for access) for further information regarding PRMC Reviews.
  5. After PRMC approval is obtained, the research protocol should be submitted to the IRB (with the PRMC approval notice included in the submission). Contact the Health Sciences IRB Office (608-263-2362) with questions.
  6. After PRMC and IRB approval has been received, please submit the Formal Biospecimen Request Form via iLab and email a copy of the approved IRB protocol to the TSB Program Manager.
  7. Biospecimen disbursement will usually occur within two weeks of receiving the Formal Biospecimen Request and approved IRB protocol.

TMA Request

Descriptions and fees are listed separately for each type of tissue microarray (TMA) currently available. Please review the information in advance to determine if the TMA is adequate for your research.

Follow these instructions for requesting TMA slides:

  1. Complete the TMA Slide Request For Services form via iLab
  2. Email the completed form to the TSB BioBank at biobank@uwcarbone.wisc.edu.
  3. The TSB BioBank Facility Manager will inform you if there is sufficient TMA available. If the requested TMA is available, the research proposal will be reviewed by the TSB BioBank Faculty Leader and Co-Leaders, along with representatives of the specific Disease Oriented Working Group. The review will include an assessment of the proprosal’s TMA request and prioritization.
  4. The TSB BioBank Facility Manager will inform the investigator of the committee’s response within 2 weeks.
  5. For requests that receive approval, disbursement of the TMA slides will usually occur within 3 weeks of submitting the request.